HPE ProLiant DL380 Gen10 24×2.5″

  • CPU: Dual (2) Intel Xeon Gold 6148 – 2.40 GHz
  • Total: 40-Cores, 80-Threads, 55 MB-Cache
  • Ram: 128GB DDR4
  • Storage: 24x (1.8 TB SAS HDD 2.5″ )
  • Raid Controller: Smart Array P816i-a
  • Lan Card: 4-Port 1GbE
  • Power Supply: Dual (2) 800W
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HPE ProLiant DL380 Gen10 24×2.5″ – Scalable and Secure Enterprise Server

The HPE ProLiant DL380 Gen10 24×2.5″ server is a secure, high-performance 2U rackmount platform engineered to deliver exceptional compute power, scalability, and storage density for modern enterprise workloads. Designed to support demanding applications such as virtualization, hybrid cloud environments, big data analytics, AI-driven workloads, and containerized infrastructures, this configuration provides enhanced storage capacity through its 24×2.5″ drive bay architecture, enabling organizations to maximize performance and storage efficiency within a compact 2U form factor.

From edge deployments to core data centers and hybrid cloud infrastructures, the HPE ProLiant DL380 Gen10 24×2.5″ offers a powerful and future-ready foundation for digital transformation. By combining enterprise-grade security technologies, intelligent system management, and optimized power efficiency, this server ensures reliability and operational continuity. Backed by HPE’s global support ecosystem and extended warranty options, it is a trusted platform for organizations that require high availability, scalability, and consistent performance.

Advanced Security Features in HPE ProLiant DL380 Gen10 24×2.5″

Security is deeply embedded in the architecture of the HPE ProLiant DL380 Gen10 24×2.5″. Through HPE Silicon Root of Trust, the server verifies firmware integrity from the very first boot cycle, protecting the infrastructure from firmware attacks and unauthorized modifications.

Key security features include:

UEFI Secure Boot and Secure Start support

Silicon Root of Trust for immutable firmware validation

Tamper-free updates with digitally signed firmware components

Secure firmware rollback and recovery capabilities

TPM 1.2 and TPM 2.0 module support

FIPS 140-2 validation and Common Criteria certification

Compliance-ready configurations for PCI DSS and CNSA security standards

Optional chassis intrusion detection and Bezel Locking Kit

These built-in security mechanisms help enterprises protect critical workloads and maintain compliance with strict regulatory and cybersecurity requirements.

Performance and Scalability

The HPE ProLiant DL380 Gen10 24×2.5″ supports dual Intel Xeon Scalable processors, providing powerful compute performance and flexibility for demanding enterprise applications. With support for large memory capacity and high-density storage configurations, the server allows organizations to scale infrastructure efficiently as business needs evolve.

Specifications:

Form Factor: 2U Rackmount

Processor: Up to 2× Intel Xeon Scalable CPUs

Memory: Up to 3TB DDR4 HPE SmartMemory at 2933 MT/s

Drive Bays: Up to 24× 2.5″ SFF drives (SAS / SATA / SSD options)

RAID Support: HPE Smart Array controllers

Expansion Slots: Multiple PCIe 3.0 slots

Management: Integrated HPE iLO 5

This combination of high compute density, expanded storage capacity, and scalable memory architecture makes the server ideal for data-intensive enterprise workloads and performance-critical applications.

Intelligent System Management

Through HPE iLO 5, the HPE ProLiant DL380 Gen10 24×2.5″ delivers advanced remote management capabilities that enable IT administrators to monitor, manage, and troubleshoot servers from virtually anywhere.

Management and security capabilities include:

Advanced remote console access

Power and thermal monitoring

Automated firmware updates and proactive alerts

AES encryption for secure communication

Role-based access control

Centralized audit logging and compliance tracking

iLO Amplifier Pack for large-scale infrastructure monitoring

HPE InfoSight with AI-driven predictive analytics

These intelligent tools reduce operational complexity, minimize downtime, and improve overall visibility across the IT environment.

Energy Efficiency and Cooling

The HPE ProLiant DL380 Gen10 24×2.5″ is designed with energy efficiency in mind. High-efficiency power supplies dynamically adapt to workload requirements, helping reduce energy consumption and operational costs. Intelligent cooling technologies, including adaptive fan control and advanced thermal sensors, ensure optimal airflow and system stability while extending hardware lifespan.

HPE’s sustainable design approach helps organizations support green IT initiatives while maintaining high performance and reliability.

Use Cases

Virtualization and VDI infrastructures

Enterprise and large-scale data centers

Mission-critical databases and ERP systems

Private and hybrid cloud environments

High-performance application hosting

Container platforms and Kubernetes environments

High-density storage deployments

Conclusion

The HPE ProLiant DL380 Gen10 24×2.5″ is a powerful, secure, and highly scalable rack server designed to support the evolving needs of modern enterprises. With its high-density 24-drive configuration, advanced security architecture, intelligent system management, and energy-efficient operation, it delivers exceptional performance and long-term value.

Whether organizations are modernizing data center infrastructure, deploying virtualized workloads, or expanding hybrid cloud capabilities, the DL380 Gen10 24×2.5″ provides the performance, flexibility, and enterprise-grade reliability required to power today’s and tomorrow’s digital environments.

For more details, you can view the data sheet on our website using the following link: Spec sheet
From factor2U
ProcessorIntel® Xeon® Scalable processors.
No. Of processor socket2
Support graphic cardNVIDIA A16 64GB PCIe Non-CEC Accelerator for HPE NVIDIA A40 48GB PCIe Non-CEC Accelerator for HPE NVIDIA A2 16GB PCIe Non-CEC Accelerator for HPE NVIDIA A40 48GB PCIe Non-CEC Accelerator for HPE NVIDIA A2 16GB PCIe Non-CEC Accelerator for HPE NVIDIA T4 16GB Computational Accelerator for HPE
Ram typeDDR4
Total Memory slots24 DIMM slots
Supported Ram8 GB, 16 GB, 32 GB, 64 GB, 128 GB
Max memoryUp to 3 TB DDR4 2933 MT/s
Pcle slots8 PCIe 3.0 slots
Support Raid controller-Software RAID HPE Smart Array S100i SR Gen10 SW RAID Essential RAID Controller HPE Smart Array E208i-a SR Gen10 Controller HPE Smart Array E208i-p SR Gen10 Controller HPE Smart Array E208e-p SR Gen10 Controller -Performance RAID Controller Broadcom MegaRAID MR416i-a Controller for HPE Broadcom MegaRAID MR416i-p Controller for HPE Broadcom MegaRAID MR216i-a Controller for HPE Broadcom MegaRAID MR216i-p Controller for HPE HPE Smart Array P408i-a SR Gen10 Controller HPE Smart Array P408i-p SR Gen10 Controller HPE Smart Array P408e-p SR Gen10 Controller HPE Smart Array P816i-a SR Gen10 Controller
Network controller1x Embedded 4 x 1GbE Network Adapter
I/o port-Serial : Optional, rear -Display port : 1 (SFF 1 front, optional via Universal Media Bay), 8 LFF chassis standard -Network ports : 4 x 1GbE embedded (if equipped/depending on model) One (1) FlexibleLOM slot available on all chassis types (supporting various NIC adapters) -Micro SD Slot : 1 Micro SD -USB 3.0 : Up to 5 total: 1 front, 2 rear, 2 internal (secure), 2 optional USB 2.0 front via Universal Media Bay, or standard on 8LFF chassis
Power supply500W , 800W , 1600W Platinum
Remote managementHPE iLO Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download); HPE iLO Advanced, HPE iLO Advanced Premium Security Edition and HPE OneView Advanced (require licenses)
Operating systemWindows Server Micrsoft Hyper-V Server VMware vSphere ClearOS Red Hat Enterprise Linux (RHEL) SUSE Linux Enterprise Server (SLES) Ubuntu Oracle Linux Citrix
DimensionsHeight : 8.73 cm(3.44 in) Width : 44.54 cm(17.54 in) Depth : 67.94 cm(26.75 in)
Weight­ Max : 19.5 kg / 43.00 lbs. ­ Min : 14.9 kg / 32.75 lbs.

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