HPE ProLiant ML350 Gen10 8×2.5″

  • CPU: Dual (2) Intel Xeon Gold 6140 – 2.30 GHz
  • Total: 36 – Cores , 72 – Threads, 49.5MB – Cache
  • Ram: 24x 16GB ECC DDR4 – [ Total 384GB ]
  • Storage: 8x ( 800GB SAS SSD )
  • Raid Controller: HPE Smart Array P408i-a SR Gen10
  • Fiber Card: HPE 562 2port 10GB X2PCS
  • Fiber card: Hp Sn1100E 2port 16GB X2PCS
  • Lan Card: 2×1GbE + 2×10GbE SFP+
  • Power Supply: Dual ( 2 ) 500W
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HPE ProLiant ML350 Gen10 8×2.5″

The HPE ProLiant ML350 Gen10 8×2.5″ is a highly flexible and secure dual-socket tower server designed to support a wide range of enterprise workloads. With its compact yet expandable chassis, this server can operate as a tower or be easily converted into a rack-mounted system, making it suitable for diverse physical environments. The HPE ProLiant ML350 Gen10 8×2.5″ is engineered to meet the evolving needs of growing SMBs, remote and branch offices, and enterprise data centers that require reliability, scalability, and long-term investment protection.

Built on the proven HPE Gen10 platform, the HPE ProLiant ML350 Gen10 8×2.5″ combines strong performance, advanced security, and flexible storage options in a single platform that grows alongside your business in the digital economy.

Performance and Processing Power

The HPE ProLiant ML350 Gen10 8×2.5″ supports up to two Intel® Xeon® Scalable processors, delivering powerful multi-core performance for demanding applications. This dual-processor architecture enables efficient handling of virtualization, database workloads, enterprise applications, and mixed-use environments.

With support for a wide range of processor families, the HPE ProLiant ML350 Gen10 8×2.5″ allows organizations to choose the optimal balance between performance, power efficiency, and cost. Advanced CPU features ensure consistent performance under sustained workloads, making the server a reliable foundation for business-critical operations.

Memory Capacity and Scalability

Memory scalability is a key strength of the HPE ProLiant ML350 Gen10 8×2.5″. The server supports up to 24 DDR4 DIMM slots, enabling large memory configurations that support memory-intensive workloads. High-speed HPE DDR4 Smart Memory improves data throughput while reducing latency, helping applications run faster and more efficiently.

This flexible memory architecture allows the HPE ProLiant ML350 Gen10 8×2.5″ to adapt easily to future growth, whether expanding virtual machine density or supporting advanced analytics and in-memory applications.

Flexible Storage and Expansion Options

The HPE ProLiant ML350 Gen10 8×2.5″ is designed with storage flexibility in mind. Its 8×2.5-inch small form factor drive configuration supports SAS and SATA drives, making it ideal for performance-focused workloads that require fast data access and efficient storage utilization.

In addition to its default drive cage, the HPE ProLiant ML350 Gen10 8×2.5″ supports expansion through optional drive cages and NVMe Express Bay options, enabling organizations to scale storage capacity and performance as requirements evolve. This modular design allows businesses to deploy the server initially with minimal configuration and expand later without replacing the platform.

RAID, Data Protection, and Reliability

Data protection is a core feature of the HPE ProLiant ML350 Gen10 8×2.5″. The server supports a wide range of HPE Smart Array RAID controllers, enabling multiple RAID levels to protect against data loss and disk failures. Advanced RAID features improve availability and performance while ensuring business continuity.

Enterprise-grade reliability is further enhanced through redundant cooling options, high-quality components, and support for hot-plug drives. These features make the HPE ProLiant ML350 Gen10 8×2.5″ suitable for environments where uptime and data integrity are critical.

Networking and Connectivity

The HPE ProLiant ML350 Gen10 8×2.5″ includes embedded network connectivity designed to meet modern enterprise requirements. Integrated network ports provide reliable connectivity out of the box, while PCIe expansion slots allow the installation of additional network adapters for higher bandwidth or specialized networking needs.

This flexible networking design ensures that the HPE ProLiant ML350 Gen10 8×2.5″ can support evolving workloads, whether deployed in a standalone environment or integrated into a larger data center infrastructure.

Security and Data Protection

Security is a defining feature of the HPE ProLiant ML350 Gen10 8×2.5″. Built on HPE’s Silicon Root of Trust, the server provides hardware-level security that protects firmware from attacks and ensures system integrity from boot to runtime.

Advanced security features such as secure boot, firmware validation, and one-button secure erase help protect sensitive data and reduce the risk of cyber threats. These capabilities make the HPE ProLiant ML350 Gen10 8×2.5″ an excellent choice for organizations with strict security and compliance requirements.

Ease of Management

Managing the HPE ProLiant ML350 Gen10 8×2.5″ is simplified through HPE Integrated Lights-Out (iLO 5). This advanced remote management solution allows administrators to monitor system health, deploy updates, and troubleshoot issues remotely, reducing operational overhead and downtime.

With support for modern management standards and integration with HPE management tools, the HPE ProLiant ML350 Gen10 8×2.5″ enables efficient lifecycle management across single-server and multi-server environments.

Use Cases

The versatility of the HPE ProLiant ML350 Gen10 8×2.5″ makes it suitable for a wide range of applications. It is ideal for file and print services, virtualization, collaboration platforms, enterprise applications, and remote office deployments.

Its ability to scale compute, memory, and storage resources ensures that the HPE ProLiant ML350 Gen10 8×2.5″ can support both current workloads and future business growth without requiring frequent hardware refreshes.

Operating System Compatibility

The HPE ProLiant ML350 Gen10 8×2.5″ supports a wide range of enterprise operating systems and virtualization platforms. It integrates seamlessly with popular environments such as VMware, Microsoft Windows Server, and major Linux distributions, allowing organizations to deploy the server within existing IT ecosystems with confidence.

Why Choose the HPE ProLiant ML350 Gen10 8×2.5″ Server

Choosing the HPE ProLiant ML350 Gen10 8×2.5″ means investing in a secure, scalable, and highly adaptable server platform. Its combination of strong performance, flexible storage, enterprise-grade security, and advanced management tools makes it a reliable solution for organizations seeking long-term value.

The server’s tower-to-rack flexibility further enhances deployment options, making the HPE ProLiant ML350 Gen10 8×2.5″ suitable for a wide range of environments and business scenarios.

Conclusion

The HPE ProLiant ML350 Gen10 8×2.5″ is a powerful and flexible enterprise server designed to grow with your business. By delivering robust performance, scalable memory and storage, advanced security, and simplified management, it provides a strong foundation for modern IT infrastructures.

For organizations looking for a dependable server that balances performance, expandability, and security, the HPE ProLiant ML350 Gen10 8×2.5″ stands out as a proven and future-ready solution

For more details, you can view the data sheet on our website using the following links: Spec Sheet

Form factor

4U

Processor

Intel Second Generation Xeon® Scalable Processors

Ram type

DDR4

Total Memory slots

24 DIMM slots

Max memory

(LRDIMM) 3 TB 24 x 128 GB LRDIMM @ 2933 MT/s
(RDIMM) 1.5 TB 24 x 64 GB RDIMM @ 2933 MT/s

PCle slots

8 PCIe Gen3 slots

Support Raid controller

Software RAID
• HPE Smart Array S100i SR Gen10 SW RAID
Essential RAID Controller
• HPE Smart Array E208i-a SR Gen10 Controller
• HPE Smart Array E208i-p SR Gen10 Controller
• HPE Smart Array E208e-p SR Gen10 Controller
Performance RAID Controller
• HPE Smart Array P408i-a SR Gen10 Controller
• HPE Smart Array P408i-p SR Gen10 Controller
• HPE Smart Array P408e-p SR Gen10 Controller
• HPE Smart Array P816i-a SR Gen10 Controller
• HPE Smart Array P824i-p MR Gen10 Controller

Network controller

4 x 1 Gb ports shipping standard, with optional stand up card

I/O Port

Serial: 1 standard (at system rear)
VGA Port: 1 standard (at system rear)
Display Port: 1 standard (at system rear)
HPE iLO Remote Management Network Port: 1 Gb Dedicated
USB 3.0/2.0: 6 total, standard: 2 front (USB 3.0), 2 rear (USB 3.0), 2 internal (1 x USB 3.0 & 1 x USB 2.0)

Power supply

HPE 500W Standard Non-Hot-Plug Power Supply Kit
HPE 500W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit
HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit
HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit

Remote managment

HPE Integrated Lights-Out (iLO 5)

Operating system

Windows Server
VMware ESXi
Linux (RHEL, SUSE) – UEFI & Legacy BIOS supported

Dimensions

• Tower
46.25 (H) x 64.8 (D) x 17.4 (W) cm 18.2 (H) x 25.51 (D) x 6.85 (W) in
• Rack – System only
17.4 (H/4U) x 64.8 (D) x 44.5 (W) cm 6.85 (H) x 25.51 (D) x 17.52 (W) in
• Tower-to-Rack Conversion Kit (1U)
4.445 (H/1U) x 69.2 (D/without CMA. Depth with CMA: 83.5) x 45.2 (W) cm 1.75 (H/1U) x 27.23 (D/without CMA. Depth with CMA: 32.89) x 17.795 (W) in

Weight

Min: 21 kg (46.30 lb)
Max: 42 kg (92.59 lb)

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